METHODS AND COMPOSITIONS COMPRISING TUMOR SUPPRESSOR GENE THERAPY FOR THE INHIBITION OF PATHOGENS

Provided herein are methods and compositions for suppressing or preventing an infection in a subject infected by a pathogen or decreasing organ or tumor tissue fibrosis that involve administering to the subject a composition that includes a therapeutically effective amount of a p53 therapy. Also dis...

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Bibliographische Detailangaben
Hauptverfasser: WIEDERHOLD, Dora, CHADA, Sunil, MENANDER, Kerstin B, SOBOL, Robert E
Format: Patent
Sprache:eng
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Zusammenfassung:Provided herein are methods and compositions for suppressing or preventing an infection in a subject infected by a pathogen or decreasing organ or tumor tissue fibrosis that involve administering to the subject a composition that includes a therapeutically effective amount of a p53 therapy. Also disclosed are methods of suppressing tumor stroma by contacting the tumor stroma with the p53 therapy, wherein the p53 suppresses tumor stroma activities.