CUTIBACTERIUM ACNES RECOMBINANT PHAGES, METHOD OF PRODUCTION AND USES THEREOF

The invention relates to C. acnes strains carrying DNA vectors for the production of recombinant C. acnes phages. The invention encompasses a C. acnes producer cell carrying DNA vectors, with a template for recombination with C. acnes phage genome leading to the insertion of a gene of interest, for...

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Bibliographische Detailangaben
Hauptverfasser: LEVEAU, Aymeric, DECRULLE, Antoine, MATHIEU, Aurélie, CANADAS BLASCO, Inès
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to C. acnes strains carrying DNA vectors for the production of recombinant C. acnes phages. The invention encompasses a C. acnes producer cell carrying DNA vectors, with a template for recombination with C. acnes phage genome leading to the insertion of a gene of interest, for the production of recombinant phages that can lead to the transgene expression into C. acnes infected by the recombinant phage. The invention encompasses, C. acnes strains containing these vectors, C. acnes recombinant phages and methods of using these recombinant phages.