ACRYLATE HYDROGEL MEMBRANE FOR DUAL FUNCTION OF DIFFUSION LIMITING MEMBRANE AS WELL AS ATTENUATION TO THE FOREIGN BODY RESPONSE

ACRYLATE HYDROGEL MEMBRANE FOR DUAL FUNCTION OF DIFFUSION LIMITING MEMBRANE AS WELL AS ATTENUATION TO THE FOREIGN BODY RESPONSE

Embodiments of the invention provide compositions useful in implantable devices such as analyte sensors as well as methods for making and using such compositions and devices. In typical embodiments of the invention, the device is a glucose sensor comprising an analyte modulating layer formed from ac...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pesantez, Daniel E, Rao, Ashwin K, Somasuntharam, Inthirai
Format: Patent
Sprache:eng
Schlagworte:
DIAGNOSIS
HUMAN NECESSITIES
HYGIENE
IDENTIFICATION
MEDICAL OR VETERINARY SCIENCE
SURGERY
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Beschreibung
Zusammenfassung:Embodiments of the invention provide compositions useful in implantable devices such as analyte sensors as well as methods for making and using such compositions and devices. In typical embodiments of the invention, the device is a glucose sensor comprising an analyte modulating layer formed from acrylate hydrogel composition that modulates the diffusion of glucose through the analyte modulating layer and which further comprises a bioactive agent selected to enhance the biocompatibility of analyte sensors when implanted in vivo.