3-HYDROXYOXINDOLE DERIVATIVES AS CRHR2 ANTAGONIST

The present invention relates to 3-hydroxyoxindole derivatives which have antagonistic activities against CRHR2, and which are useful in the treatment or prevention of disorders and diseases in which CRHR2 is involved. The invention also relates to pharmaceutical compositions comprising these compou...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ANDO, Kazuo, MAGARA, Ryohei, OHMI, Masashi
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to 3-hydroxyoxindole derivatives which have antagonistic activities against CRHR2, and which are useful in the treatment or prevention of disorders and diseases in which CRHR2 is involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CRHR2 is involved.