NOVEL SYNTHETIC PATHWAY TO BELZUTIFAN
The disclosure provides a novel process and synthetic intermediates for making belzutifan, a HIF-2a inhibitor, useful for the treatment of certain VHL-related indications and cancer.
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| creator | Winston, Matthew S McMullen, Jonathan P Morris, William McCann, Scott D McIntosh, John Zhang, Victoria Zhong, Yong-Li Chun, Stephanie W Moore, Jeffrey C Cheung-Lee, Wai Ling Kim, Jungchul Kosjek, Birgit DiRocco, Daniel A Cahn, Jackson Kenai Blender Johnson, Heather Claire Hethcox, J. Caleb Kolev, Joshua N Le, Diane Velasquez Velez, Juan Esteban |
| description | The disclosure provides a novel process and synthetic intermediates for making belzutifan, a HIF-2a inhibitor, useful for the treatment of certain VHL-related indications and cancer. |
| format | Patent |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | NOVEL SYNTHETIC PATHWAY TO BELZUTIFAN |
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