METHOD FOR PRODUCING PROTEIN COMPOSITIONS

The present invention generally relates to the provision of means and methods for preparing protein compositions. The invention provides a method comprising the steps of (i) contacting a starting composition comprising a protein with a hydrolase inhibitor, wherein the hydrolase inhibitor is immobili...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LEISS, Michael, FALKENSTEIN, Roberto, REMPT, Martin, EDELMANN, Franziska, WEDEKIND, Frank, GRAF, Tobias
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention generally relates to the provision of means and methods for preparing protein compositions. The invention provides a method comprising the steps of (i) contacting a starting composition comprising a protein with a hydrolase inhibitor, wherein the hydrolase inhibitor is immobilized on a solid carrier; (ii) recovering a composition comprising the protein. Furthermore, the invention relates to a method for preparing a protein formulation comprising the steps of (i) contacting a starting composition comprising a protein with a hydrolase inhibitor, wherein the hydrolase inhibitor is immobilized on a solid carrier; (ii) recovering a composition comprising the protein, wherein the method for preparing the protein formulation further comprises adding a surfactant, preferably a fatty acid ester, to the composition comprising the protein. Moreover, the invention relates to a protein composition obtained or obtainable by the methods described herein and/or to a protein formulation obtained or obtainable by the methods described herein.