PED5 INHIBITOR SEMI-SOLID COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF

A chewable composition comprising an active pharmaceutical ingredient (API) composition, a surfactant composition, a binding composition, and a gelling composition in a sufficient amount to provide a cohesive gelled product. The API composition comprises a PED5 inhibitor; the surfactant composition...

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Bibliographische Detailangaben
Hauptverfasser: WAN, Feng, Carlson, William Brenden
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A chewable composition comprising an active pharmaceutical ingredient (API) composition, a surfactant composition, a binding composition, and a gelling composition in a sufficient amount to provide a cohesive gelled product. The API composition comprises a PED5 inhibitor; the surfactant composition and the API composition have a weight ration from about 0.1 to about 15; and the binding composition comprises a mono- or di-saccharide, a sugar alcohol, an oligosaccharide, or a combination thereof. In one embodiment, the API composition comprises tadalafil, sildenafil, vardenafil, avanafil, or a combination thereof.