COVALENT CDK2-BINDING COMPOUNDS FOR THERAPEUTIC PURPOSES

Heteroaryl sulfonyl compounds and compositions that have a CDK2 Recognition Moiety bound to an electrophile for the selective covalent modification of CDK2 to treat CDK2-mediated disorders are described.

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Bibliographische Detailangaben
Hauptverfasser: Barbe, Guillaume, Sauliner, Mark George, Greenlee, William John, Ray, Soumya
Format: Patent
Sprache:eng
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Zusammenfassung:Heteroaryl sulfonyl compounds and compositions that have a CDK2 Recognition Moiety bound to an electrophile for the selective covalent modification of CDK2 to treat CDK2-mediated disorders are described.