[6,6] FUSED BICYCLIC HDAC8 INHIBITORS

The present invention is directed to compounds of Formula I:and pharmaceutically acceptable salts, prodrugs, solvates, hydrates, tautomers, or isomers or thereof, wherein R1, R2, R2′, L, X, W, Y1, Y2, Y3, and Y4 are described herein.

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Bibliographische Detailangaben
Hauptverfasser: Lancia, JR., David R, Han, Bingsong, Barczak, Nicholas, Bair, Kenneth W, Zablocki, Mary-Margaret, Ng, Pui Yee, Liu, Cuixian, Rudnitskaya, Aleksandra, Zheng, Xiaozhang, Downing, Jennifer R
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to compounds of Formula I:and pharmaceutically acceptable salts, prodrugs, solvates, hydrates, tautomers, or isomers or thereof, wherein R1, R2, R2′, L, X, W, Y1, Y2, Y3, and Y4 are described herein.