GASTRORETENTIVE DOSAGE FORMS FOR SUSTAINED DRUG DELIVERY

The present disclosure is directed to floating gastroretentive dosage forms with prolonged gastric residence time. The disclosure also provides rapidly expanding sustained release or combined immediate release and sustained release formulations comprising drugs that require targeted release in the p...

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Bibliographische Detailangaben
Hauptverfasser: Desai, Dipen, Shelke, Namdev B, Chatterji, Ashish, Meghpara, Kanji, Vagashiya, Jaydeep, Phuapradit, Wantanee, Sandhu, Harpreet Kaur, Shah, Navnit H, Vaka, Siva Ram Kiran
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure is directed to floating gastroretentive dosage forms with prolonged gastric residence time. The disclosure also provides rapidly expanding sustained release or combined immediate release and sustained release formulations comprising drugs that require targeted release in the proximal gastrointestinal tract for maximum therapeutic benefit. The rapidly expanding floating gastroretentive dosage forms comprise a permeable elastic membrane providing desired characteristics for drug release and mechanical strength to maintain tablet integrity.