Method, Compositions and Applications of Mechanosensitive Channels

The present invention generally relates to the novel method, compositions and applications of mechanosensitive channels in therapeutics for visual, neurological and other disorders. Specifically, the invention relates to exploitation of mechanosensitive channels' intrinsic property as a transge...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Dibas, Adnan, Batabyal, Subrata, Narcisse, Darryl, Mohanty, Samarendra Kumar, Idigo, Chinenye Abiodun
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator Dibas, Adnan
Batabyal, Subrata
Narcisse, Darryl
Mohanty, Samarendra Kumar
Idigo, Chinenye Abiodun
description The present invention generally relates to the novel method, compositions and applications of mechanosensitive channels in therapeutics for visual, neurological and other disorders. Specifically, the invention relates to exploitation of mechanosensitive channels' intrinsic property as a transgenic pressure modulator and alternative outflow actuator in the treatment of different diseases such as glaucoma, blood pressure and other diseases involving of cells prone to mechanical or osmotic stress. Furthermore, the invention relates to exploitation of mechanosensitive channels for stimulation of cells enabling therapies for different diseases including pain, as well as molecular delivery to cells triggered by internal and/or external mechanical stimuli.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2023382955A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2023382955A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2023382955A13</originalsourceid><addsrcrecordid>eNrjZHDyTS3JyE_RUXDOzy3IL84syczPK1ZIzEtRcCwoyMlMToQI5Kcp-KYmZyTm5Ren5oFUlaUqOAO5eak5xTwMrGmJOcWpvFCam0HZzTXE2UM3tSA_PrW4IDE5NS-1JD402MjAyNjYwsjS1NTR0Jg4VQAQ-zMv</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Method, Compositions and Applications of Mechanosensitive Channels</title><source>esp@cenet</source><creator>Dibas, Adnan ; Batabyal, Subrata ; Narcisse, Darryl ; Mohanty, Samarendra Kumar ; Idigo, Chinenye Abiodun</creator><creatorcontrib>Dibas, Adnan ; Batabyal, Subrata ; Narcisse, Darryl ; Mohanty, Samarendra Kumar ; Idigo, Chinenye Abiodun</creatorcontrib><description>The present invention generally relates to the novel method, compositions and applications of mechanosensitive channels in therapeutics for visual, neurological and other disorders. Specifically, the invention relates to exploitation of mechanosensitive channels' intrinsic property as a transgenic pressure modulator and alternative outflow actuator in the treatment of different diseases such as glaucoma, blood pressure and other diseases involving of cells prone to mechanical or osmotic stress. Furthermore, the invention relates to exploitation of mechanosensitive channels for stimulation of cells enabling therapies for different diseases including pain, as well as molecular delivery to cells triggered by internal and/or external mechanical stimuli.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20231130&amp;DB=EPODOC&amp;CC=US&amp;NR=2023382955A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20231130&amp;DB=EPODOC&amp;CC=US&amp;NR=2023382955A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Dibas, Adnan</creatorcontrib><creatorcontrib>Batabyal, Subrata</creatorcontrib><creatorcontrib>Narcisse, Darryl</creatorcontrib><creatorcontrib>Mohanty, Samarendra Kumar</creatorcontrib><creatorcontrib>Idigo, Chinenye Abiodun</creatorcontrib><title>Method, Compositions and Applications of Mechanosensitive Channels</title><description>The present invention generally relates to the novel method, compositions and applications of mechanosensitive channels in therapeutics for visual, neurological and other disorders. Specifically, the invention relates to exploitation of mechanosensitive channels' intrinsic property as a transgenic pressure modulator and alternative outflow actuator in the treatment of different diseases such as glaucoma, blood pressure and other diseases involving of cells prone to mechanical or osmotic stress. Furthermore, the invention relates to exploitation of mechanosensitive channels for stimulation of cells enabling therapies for different diseases including pain, as well as molecular delivery to cells triggered by internal and/or external mechanical stimuli.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHDyTS3JyE_RUXDOzy3IL84syczPK1ZIzEtRcCwoyMlMToQI5Kcp-KYmZyTm5Ren5oFUlaUqOAO5eak5xTwMrGmJOcWpvFCam0HZzTXE2UM3tSA_PrW4IDE5NS-1JD402MjAyNjYwsjS1NTR0Jg4VQAQ-zMv</recordid><startdate>20231130</startdate><enddate>20231130</enddate><creator>Dibas, Adnan</creator><creator>Batabyal, Subrata</creator><creator>Narcisse, Darryl</creator><creator>Mohanty, Samarendra Kumar</creator><creator>Idigo, Chinenye Abiodun</creator><scope>EVB</scope></search><sort><creationdate>20231130</creationdate><title>Method, Compositions and Applications of Mechanosensitive Channels</title><author>Dibas, Adnan ; Batabyal, Subrata ; Narcisse, Darryl ; Mohanty, Samarendra Kumar ; Idigo, Chinenye Abiodun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2023382955A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Dibas, Adnan</creatorcontrib><creatorcontrib>Batabyal, Subrata</creatorcontrib><creatorcontrib>Narcisse, Darryl</creatorcontrib><creatorcontrib>Mohanty, Samarendra Kumar</creatorcontrib><creatorcontrib>Idigo, Chinenye Abiodun</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Dibas, Adnan</au><au>Batabyal, Subrata</au><au>Narcisse, Darryl</au><au>Mohanty, Samarendra Kumar</au><au>Idigo, Chinenye Abiodun</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Method, Compositions and Applications of Mechanosensitive Channels</title><date>2023-11-30</date><risdate>2023</risdate><abstract>The present invention generally relates to the novel method, compositions and applications of mechanosensitive channels in therapeutics for visual, neurological and other disorders. Specifically, the invention relates to exploitation of mechanosensitive channels' intrinsic property as a transgenic pressure modulator and alternative outflow actuator in the treatment of different diseases such as glaucoma, blood pressure and other diseases involving of cells prone to mechanical or osmotic stress. Furthermore, the invention relates to exploitation of mechanosensitive channels for stimulation of cells enabling therapies for different diseases including pain, as well as molecular delivery to cells triggered by internal and/or external mechanical stimuli.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2023382955A1
source esp@cenet
subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Method, Compositions and Applications of Mechanosensitive Channels
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-21T20%3A33%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Dibas,%20Adnan&rft.date=2023-11-30&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2023382955A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true