COVALENT CONJUGATES OF THE SARS-COV-2 RECEPTOR-BINDING DOMAIN AND A CARRIER PROTEIN AND VACCINE COMPOSITIONS THAT CONTAIN THEM

This invention pertains to biotechnology, more specifically to the field of human health. This document describes in particular conjugates of the SARS-CoV-2 receptor binding domain covalently conjugated to a carrier protein, the method used to obtain them, and the vaccine compositions that contain t...

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Hauptverfasser: García Ricardo, Manuel, García Rivera, Daniel, Ojito Magaz, Eduardo, Boggiano Ayo, Tammy, García Rivera, Dagmar, Valdés Balbín, Yury, Ramírez González, Ubel Jesús, Oliva Hernández, Reynaldo, Santana Mederos, Darielys, Rodríguez Noda, Laura Marta, Fernández Castillo, Sonsire, Sánchez Ramírez, Belinda, Verez Bencomo, Vicente Guillermo
Format: Patent
Sprache:eng
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Zusammenfassung:This invention pertains to biotechnology, more specifically to the field of human health. This document describes in particular conjugates of the SARS-CoV-2 receptor binding domain covalently conjugated to a carrier protein, the method used to obtain them, and the vaccine compositions that contain them. The vaccine compositions described in this invention are useful for the prevention of the SARS-CoV-2 infection as they induce a strong response of neutralizing antibodies.