PREPARING AND USE OF GLU-PLASMINOGEN FROM BLOOD FRACTIONS

The present invention relates to a method for isolating Glu-plasminogen, said method comprising the anion exchange chromatography of blood plasma or a plasma fraction comprising Glu-plasminogen. Furthermore, the present invention relates to Glu-plasminogen obtainable from the method of the present i...

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Bibliographische Detailangaben
Hauptverfasser: Karges, Hermann E, Kiessig, Stephan T, Gerding, Hanne Rieke, Welz, Ricarda, Mazur, Marc
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a method for isolating Glu-plasminogen, said method comprising the anion exchange chromatography of blood plasma or a plasma fraction comprising Glu-plasminogen. Furthermore, the present invention relates to Glu-plasminogen obtainable from the method of the present invention and its use in a method for treating a patient suffering from or being at risk of developing a disorder selected from the group consisting of organ failure, a thrombotic event, arterial obstructive disease, microcirculation, disseminated intravascular coagulation (DIC), and a combination of two or more thereof.