A LIQUID INJECTABLE COMPOSITION OF DONEPEZIL

A liquid injectable composition comprising:(a) a bioerodible and biodegradable, release retardant polymer comprising polylactic-ccs-glycolic acid) (PLEA), polylactide (PLA), or combination thereof;(b) a biocompatible solvent selected from dimethylsulfoxide, 2-pyrrolidone, N,N-dimethyl acetamide, dim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	SHEVADE, Sukhada Satish, VENKITACHALAM, Devarajan Padma, SUDHAKAR, Paul T, RUSTOMJEE, Maharukh T
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	A liquid injectable composition comprising:(a) a bioerodible and biodegradable, release retardant polymer comprising polylactic-ccs-glycolic acid) (PLEA), polylactide (PLA), or combination thereof;(b) a biocompatible solvent selected from dimethylsulfoxide, 2-pyrrolidone, N,N-dimethyl acetamide, dimethylformamide, glycofurol, glycerol formal, propylene glycol, benzyl benzoate, N-methyl-2-pyrrolidone, benzyl alcohol, or combination thereof; and(c) donepezil, in the free base or pharmaceutically acceptable salts thereof.