SELF-TARGETING EXPRESSION VECTOR

The present invention concerns new nucleic acid molecules which may be used in many applications, and methods for making the same. These nucleic acid molecules are preferably DNA vectors, optionally DNA expression vectors. The nucleic acid molecules are able to target the vector to a specific cellul...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ROTHWELL, Paul James, LEGIEWICZ, Michal, QUINTANEIRO, Leonor Maximo, ADIE, Thomas Antony James
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention concerns new nucleic acid molecules which may be used in many applications, and methods for making the same. These nucleic acid molecules are preferably DNA vectors, optionally DNA expression vectors. The nucleic acid molecules are able to target the vector to a specific cellular location, such as the nucleus, due to the presence of one or more particular binding motifs within the nucleic acid molecule itself. Thus, the nucleic acid molecules of the invention may also be described as targeted delivery vectors, notably self-targeted delivery vectors or smart delivery vectors.