PREPARATION METHOD AND USE OF PYRAZOLE COMPOUND CONTAINING 1-(3,4-DIMETHOXYPHENYL)-BETA-CARBOLINE UNIT

The disclosure relates to a preparation method and use of a pyrazole compound containing 1-(3,4-dimethoxyphenyl)-β-carboline unit. The pyrazole compound is prepared by reacting pyrazole aldehyde and 1-(3,4-dimethoxyphenyl)-β-carboline acylhydrazine. The pyrazole compound containing 1-(3,4-dimethoxyp...

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Hauptverfasser: ZHOU, Beibei, DAI, Hong, HUANG, Meiling, WANG, Yang, ZHANG, Yan, ZHANG, Haijun, MIAO, Heyi, QIAN, Cheng, ZHENG, Dandan, WANG, Yong
Format: Patent
Sprache:eng
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Zusammenfassung:The disclosure relates to a preparation method and use of a pyrazole compound containing 1-(3,4-dimethoxyphenyl)-β-carboline unit. The pyrazole compound is prepared by reacting pyrazole aldehyde and 1-(3,4-dimethoxyphenyl)-β-carboline acylhydrazine. The pyrazole compound containing 1-(3,4-dimethoxyphenyl)-β-carboline unit has good inhibitory activity against tumor cell HGC-27. The pyrazole compound could be used in the preparation of anti-tumor drugs.