COMPOSITION FOR PREVENTING OR TREATING OBESITY-RELATED DISEASE CONTAINING AMPHIREGULIN-SPECIFIC DOUBLE-STRANDED OLIGONUCLEOTIDE STRUCTURE

The present invention relates to a double-stranded oligonucleotide capable of inhibiting amphiregulin expression in a very specific and highly efficient manner, preferably a double-stranded oligonucleotide comprising a sequence in the form of an RNA/RNA, DNA/DNA or DNA/RNA hybrid, and the use of a d...

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Bibliographische Detailangaben
Hauptverfasser: KIM, Tae Rim, YUN, Sung Il, KIM, Jangseon, JUNG, Sang Hyuk, LEE, Mi Sun, CHOI, Soonja, SONG, Kang, SON, Seung Seob, HWANG, Soo Hyun, PARK, Han-Oh, PARK, Jun Hong
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to a double-stranded oligonucleotide capable of inhibiting amphiregulin expression in a very specific and highly efficient manner, preferably a double-stranded oligonucleotide comprising a sequence in the form of an RNA/RNA, DNA/DNA or DNA/RNA hybrid, and the use of a double-stranded oligonucleotide structure, which comprises the double-stranded oligonucleotide, and nanoparticles, for preventing or treating obesity.