SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS

The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity, and/or modulate a gene expression pathway. Specifically, the invention relates to double...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Carr, Brian Allen, Tellers, David M, Kenski, Denise M, Jadhav, Vasant R, Willingham, Aarron T
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity, and/or modulate a gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against target gene expression.