Heteroaryl Derivative, Preparation Method Therefor, And Use Thereof

The present invention relates to heteroaryl derivatives, preparation methods therefor, and applications thereof in medicine. Specifically, the present invention relates to a heteroaryl derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutically acceptable sa...

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Bibliographische Detailangaben
Hauptverfasser:	Cao, Hai, Wang, Xin, Liao, Weiwei, Chen, Lei, Hu, Taishan, Shen, Weichao, Meng, Lichen, Huang, Xiangui, Cao, Qi, Bie, Pingyan, Qiu, Zongxing, Li, Wenpeng, Ye, Cheng, Wu, Nuoyi, Yan, Qingyan, Xing, Qingna, Guo, Yanghui
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to heteroaryl derivatives, preparation methods therefor, and applications thereof in medicine. Specifically, the present invention relates to a heteroaryl derivative represented by general formula (AI), a preparation method therefor, and a pharmaceutically acceptable salt, and use thereof as a therapeutic agent, in particular, as an SHP2 allosteric inhibitor, wherein the definition of substituents in general formula (AI) is the same as that in the description.