TREATMENT OF CLL

The present invention relates to anti-BAFFR antibodies or binding fragments thereof, alone or in combination with BTK inhibitors, for use in the treatment of CLL. Specifically, the invention relates to a pharmaceutical combination comprising a BTK inhibitor, or a pharmaceutically acceptable salt the...

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Bibliographische Detailangaben
Hauptverfasser:	GOU, Liangke, HASSOUNAH, Nadia, WOO, Janghee
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to anti-BAFFR antibodies or binding fragments thereof, alone or in combination with BTK inhibitors, for use in the treatment of CLL. Specifically, the invention relates to a pharmaceutical combination comprising a BTK inhibitor, or a pharmaceutically acceptable salt thereof, and an anti-BAFFR antibody or binding fragment thereof, and their use in the treatment of CLL. The invention also relates to a method for the treatment of CLL that involves administering the combination; and to the use of the combination for the manufacture of a medicament for the treatment of CLL.