Bicyclic-Fused Heteroaryl or Aryl Compounds

Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia,as defined in the specification. In an embodiment, a pharmaceutical composition can be in a liquid dosage form and can comprise a therapeutically effectiv...

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Hauptverfasser: BUNNAGE, MARK EDWARD, LOWE, MICHAEL DENNIS, LOVERING, FRANK ELDRIDGE, LEE, ARTHUR, PATNY, AKSHAY, SAIAH, EDDINE, PAPAIOANNOU, NIKOLAOS, ZAPF, CHRISTOPH WOLFGANG, LEE, KATHERINE LIN, PIERCE, BETSY SUSAN, VARGAS, RICHARD, TRZUPEK, JOHN DAVID, HAN, SEUNGIL, GOLDBERG, JOEL ADAM, HUANG, HORNGIH, HEPWORTH, DAVID, MATHIAS, JOHN PAUL, WANG, XIAOLUN, STROHBACH, JOSEPH WALTER, ANDERSON, DAVID RANDOLPH, WRIGHT, STEPHEN WAYNE, GAVRIN, LORI KRIM, CURRAN, KEVIN JOSEPH, DEHNHARDT, CHRISTOPH MARTIN
Format: Patent
Sprache:eng
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Zusammenfassung:Compounds, tautomers and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula Ia,as defined in the specification. In an embodiment, a pharmaceutical composition can be in a liquid dosage form and can comprise a therapeutically effective amount of the compound or a pharmaceutically acceptable salt thereof as an adjuvant and a therapeutic agent. In another embodiment, a method of adjuvant treating a disorder or condition can comprising administering the pharmaceutical composition to a patient.