USE OF HIGH MOLECULAR WEIGHT HYALURONIC ACID AS OCULAR TRANSPORTING VEHICLE

The present invention concerns the use of very high molecular weight hyaluronic acid (HMWHA) as a transporting vehicle for bioactive agents, such as ophthalmic drugs and other active pharmaceutical ingredients (API), with minimized side effects. An aspect of the invention includes an ophthalmic drug...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser:	MÜLLER-LIERHEIM, WOLFGANG GEORG KONRAD
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention concerns the use of very high molecular weight hyaluronic acid (HMWHA) as a transporting vehicle for bioactive agents, such as ophthalmic drugs and other active pharmaceutical ingredients (API), with minimized side effects. An aspect of the invention includes an ophthalmic drug-delivery system (ODS) comprising HMWHA fluid and a bioactive agent, wherein the hyaluronic acid has an intrinsic viscosity of at least 2.5 m3/kg, and the HMWHA fluid is capable of transporting the bioactive agent into the eye; a method for delivering a bioactive agent into the eye; a method for treating, preventing, and/or delaying the onset or recurrence of an eye disorder in a human or animal subject; and a kit useful for carrying out the methods of the invention.