A SYSTEM TO IMPROVE HAEMOSTATIC CONTROL

The present invention relates to a safe and efficient system to improve haemostatic control by immobilization of Tissue Factor protein to a dressing material suitable for use as or in a wound dressing, bringing Tissue Factor in direct contact to the wound. The present invention aims at using immobil...

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Bibliographische Detailangaben
Hauptverfasser:	Nielsen, Peter Aadal, Osther, Kurt Baekgaard, Winther, Lars, Videbaek, Charlotte
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to a safe and efficient system to improve haemostatic control by immobilization of Tissue Factor protein to a dressing material suitable for use as or in a wound dressing, bringing Tissue Factor in direct contact to the wound. The present invention aims at using immobilized Tissue Factor to generate a "thrombin burst", a process by which thrombin, the most important constituent of the coagulation cascade is released very rapidly. There is no systemic release of the protein Tissue Factor into the vascular bed. The linked protein Tissue Factor can be used alone or in combination with other human proteins or components to optimise haemostasis.