PLASMID SYSTEM

The present invention relates to helper plasmids and two-plasmid systems for producing recombinant AAV (rAAV) vectors. The invention further relates to methods of using, or uses of the helper plasmids and two-plasmid systems of the invention. The present invention also relates to a helper plasmid wh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schulze, Andreas, Finkbeiner, Bettina, Sonntag, Florian, Hörer, Markus
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to helper plasmids and two-plasmid systems for producing recombinant AAV (rAAV) vectors. The invention further relates to methods of using, or uses of the helper plasmids and two-plasmid systems of the invention. The present invention also relates to a helper plasmid which does not comprise a cap gene encoding a functional set of Cap proteins and which does comprise at least one rep gene and at least one helper virus gene.