FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME

FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME

The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment...

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Hauptverfasser: Ding, Sheng, Wang, Deping, Geething, Nathan, Wang, Chia-wei, Schellenberger, Volker, Toby, Garabet G, Liu, Tongyao, Peters, Robert, Jiang, Haiyan, Mei, Baisong, Chang, Pei-Yun, Stemmer, Willem P, Kulman, John, Silverman, Joshua, Spink, Benjamin, Varfaj, Fatbardha
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CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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creator Ding, Sheng
Wang, Deping
Geething, Nathan
Wang, Chia-wei
Schellenberger, Volker
Toby, Garabet G
Liu, Tongyao
Peters, Robert
Jiang, Haiyan
Mei, Baisong
Chang, Pei-Yun
Stemmer, Willem P
Kulman, John
Silverman, Joshua
Spink, Benjamin
Varfaj, Fatbardha
description The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.
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subjects CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME
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