FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME

FACTOR VIII COMPOSITIONS AND METHODS OF MAKING AND USING SAME

The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment...

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Bibliographische Detailangaben
Hauptverfasser: Ding, Sheng, Wang, Deping, Geething, Nathan, Wang, Chia-wei, Schellenberger, Volker, Toby, Garabet G, Liu, Tongyao, Peters, Robert, Jiang, Haiyan, Mei, Baisong, Chang, Pei-Yun, Stemmer, Willem P, Kulman, John, Silverman, Joshua, Spink, Benjamin, Varfaj, Fatbardha
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present invention relates to compositions comprising factor VIII coagulation factors linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of making and using such compositions in treatment of factor VIII-related diseases, disorders, and conditions.