PROTEINS, POLYNUCLEOTIDES, AND METHODS FOR TREATING CORONAVIRUS INFECTION

PROTEINS, POLYNUCLEOTIDES, AND METHODS FOR TREATING CORONAVIRUS INFECTION

Provided herein are proteins that include different combinations of structural and nonstructural proteins from SARS-CoV-2 and MERS-CoV. Also provided are polynucleotides encoding the proteins of the present disclosure. In one embodiment, a polynucleotide encoding a protein is present as a viral vect...

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Bibliographische Detailangaben
Hauptverfasser: Chopra, Ashok K, Sha, Jian, Rothe, Eric, Patel, Snehal
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Provided herein are proteins that include different combinations of structural and nonstructural proteins from SARS-CoV-2 and MERS-CoV. Also provided are polynucleotides encoding the proteins of the present disclosure. In one embodiment, a polynucleotide encoding a protein is present as a viral vector, such as adenovirus. In one embodiment, a polynucleotide encoding a protein is present as a mRNA. Also provided are methods for using the proteins and polynucleotides of the present disclosure.