ANTI-TMPRSS6 ANTIBODIES AND USES THEREOF

ANTI-TMPRSS6 ANTIBODIES AND USES THEREOF

Antibodies and antigen-binding fragments thereof that bind type II transmembrane serine protease 6 (TMPRSS6) on the surface of a cell and increase hepcidin expression, and methods for treating disorders of iron metabolism and myeloproliferative disorders using anti TMPRSS6 antibodies and fragments,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHEN, BUXIN, WANG, YU JEAN, DU, XIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Antibodies and antigen-binding fragments thereof that bind type II transmembrane serine protease 6 (TMPRSS6) on the surface of a cell and increase hepcidin expression, and methods for treating disorders of iron metabolism and myeloproliferative disorders using anti TMPRSS6 antibodies and fragments, are provided.