OPEN-TOP MICROFLUIDIC DEVICE WITH STRUCTURAL ANCHORS

A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is partic...

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Bibliographische Detailangaben
Hauptverfasser: Lucchesi, Carol, Williamson, Lina, Hinojosa, Christopher David, Hamilton, Geraldine, Levner, Daniel, Varone, Antonio, Wen, Norman, Kerns, S. Jordan, Karalis, Catherine, Nguyen, Justin
Format: Patent
Sprache:eng
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Zusammenfassung:A microfluidic device is contemplated comprising an open-top cavity with structural anchors on the vertical wall surfaces that serve to prevent gel shrinkage-induced delamination, a porous membrane (optionally stretchable) positioned in the middle over a microfluidic channel(s). The device is particularly suited to the growth of cells mimicking dermal layers.