APPARATUS AND METHODS FOR POINT-OF-CARE RED BLOOD CELL WASHING

Apparatus and methods for point-of-care red blood cell washing are disclosed. One method of filtering a suspension of red blood cells may generally comprise introducing a wash solution to the suspension of red blood cells such that a combined volume is retained within a first compartment, applying a...

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Bibliographische Detailangaben
Hauptverfasser: DORIAN, Randy, KING, Scott R, STORRS, Richard W, LEACH, Michael D
Format: Patent
Sprache:eng
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Zusammenfassung:Apparatus and methods for point-of-care red blood cell washing are disclosed. One method of filtering a suspension of red blood cells may generally comprise introducing a wash solution to the suspension of red blood cells such that a combined volume is retained within a first compartment, applying a sweeping action upon the volume, applying a pressure upon the volume while applying the sweeping action such that the volume is urged through a filter membrane at a predetermined filtration rate, maintaining the filtration rate over a predetermined period of time such that hemolysis is maintained below a threshold level, and collecting the volume within a second compartment.