DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS

A series of substituted 4,4-difluorocyclohexyl derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.

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Bibliographische Detailangaben
Hauptverfasser:	HASLETT, Gregory William, HUTCHINGS, Martin Clive, QUINCEY, Joanna Rachel, VAIDYA, Darshan Gunvant, MONCK, Nathaniel Julius Thomas, JOHNSON, James Andrew, CHOVATIA, Prafulkumar Tulshibhai, SMALLEY, Adam Peter, FOLEY, Anne Marie, TRANI, Giancarlo, REUBERSON, James Thomas, LECOMTE, Fabien Claude, RAMPALAKOS, Konstantinos
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	A series of substituted 4,4-difluorocyclohexyl derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.