LIPOSOMAL FORMULATIONS FOR INHIBITING SARS-CoV-2 REPLICATION AND REDUCING LUNG INFLAMMATION

LIPOSOMAL FORMULATIONS FOR INHIBITING SARS-CoV-2 REPLICATION AND REDUCING LUNG INFLAMMATION

In some aspects, provided herein are compositions of and methods for utilizing a sterically stabilized liposome carrier encapsulating a selected drug for the delivery of such drug effectual in the treatment of a mammal infected by a virus, such as SARS-COV-2, specifically in inhibiting the viral rep...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kameswari, Konduri S, Pattisapu, Jogi, Zwetchkenbaum, John, Duzgunes, Nejat, Pattisapu, Ram
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:In some aspects, provided herein are compositions of and methods for utilizing a sterically stabilized liposome carrier encapsulating a selected drug for the delivery of such drug effectual in the treatment of a mammal infected by a virus, such as SARS-COV-2, specifically in inhibiting the viral replication and reducing symptoms including lung inflammation. The compositions and methods disclosed herein provide a potential treatment for COVID-19 with improved patient compliance as they offer a less frequent dosing for the "long haulers" post COVID-19 initial infection.