ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF ISOTRETINOIN

ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF ISOTRETINOIN

The present invention relates to new stable oral liquid pharmaceutical compositions comprising isotretinoin (13-cis retinoic acid), pharmaceutically accepted salts thereof, or other suitable isotretinoin compounds. The compositions are formulated in a lipid carrier, typically comprising phospholipid...

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Hauptverfasser: Shaik, Mahaboob Basha, Gota, Vikram Prakash, Chinnaswamy, Girish, Joshi, Mahendra R, Banavali, Shripad D, Kakkar, Archana Khosa, Mandapati, Ravindhar Reddy
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Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator Shaik, Mahaboob Basha
Gota, Vikram Prakash
Chinnaswamy, Girish
Joshi, Mahendra R
Banavali, Shripad D
Kakkar, Archana Khosa
Mandapati, Ravindhar Reddy
description The present invention relates to new stable oral liquid pharmaceutical compositions comprising isotretinoin (13-cis retinoic acid), pharmaceutically accepted salts thereof, or other suitable isotretinoin compounds. The compositions are formulated in a lipid carrier, typically comprising phospholipids, and in embodiments comprising a substantial amount of one or more phosphatidylcholines. Such compositions can further comprise a surfactant component, a medium chain triglyceride component, an antioxidant/preservative component, or combination thereof. The present invention also provides the process of preparation of such compositions and methods of using such compositions in the treatment of various diseases/conditions.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF ISOTRETINOIN
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