ORAL LIQUID PHARMACEUTICAL COMPOSITIONS OF ISOTRETINOIN

The present invention relates to new stable oral liquid pharmaceutical compositions comprising isotretinoin (13-cis retinoic acid), pharmaceutically accepted salts thereof, or other suitable isotretinoin compounds. The compositions are formulated in a lipid carrier, typically comprising phospholipid...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	Shaik, Mahaboob Basha, Gota, Vikram Prakash, Chinnaswamy, Girish, Joshi, Mahendra R, Banavali, Shripad D, Kakkar, Archana Khosa, Mandapati, Ravindhar Reddy
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention relates to new stable oral liquid pharmaceutical compositions comprising isotretinoin (13-cis retinoic acid), pharmaceutically accepted salts thereof, or other suitable isotretinoin compounds. The compositions are formulated in a lipid carrier, typically comprising phospholipids, and in embodiments comprising a substantial amount of one or more phosphatidylcholines. Such compositions can further comprise a surfactant component, a medium chain triglyceride component, an antioxidant/preservative component, or combination thereof. The present invention also provides the process of preparation of such compositions and methods of using such compositions in the treatment of various diseases/conditions.