DRUG DELIVERY DEVICES WITH ON-BOARD DRUG DESTRUCTION

Various exemplary drug delivery devices with on-board drug destruction, drug products utilizing the same, and methods of using drug delivery devices with on-board drug destruction are provided. In general, a nasal drug delivery device configured to dispense a drug therefrom into a nose includes a de...

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Hauptverfasser: YAN, Hong, ALBERTINI, Francesco N, POPLI, Shagun, CANNAMELA, Michael, WANG, Jingli, KALIKHMAN, David, KRULEVITCH, Peter, BARATTA, Michael A, ZHAO, MingQi, SCRIMGEOUR, Ian, RAMOS, David, SINGH, Jaskaran, HUBERT, Emma Louise, KAPIL, Monica A, VESOLE, Steven M, PHILLIPS, Whitney
Format: Patent
Sprache:eng
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Zusammenfassung:Various exemplary drug delivery devices with on-board drug destruction, drug products utilizing the same, and methods of using drug delivery devices with on-board drug destruction are provided. In general, a nasal drug delivery device configured to dispense a drug therefrom into a nose includes a destruction mechanism configured to destroy drug contained in the drug delivery device. The destruction mechanism can be configured to destroy the drug before a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug contained in the drug delivery device. Alternatively or in addition, the destruction mechanism can be configured to destroy the drug after a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug remaining in the drug delivery device.