SYSTEMS AND METHODS OF DETECTING DENSELY-PACKED ANALYTES

SYSTEMS AND METHODS OF DETECTING DENSELY-PACKED ANALYTES

Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. These may have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy of poly...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BALLINGER, Dennis, BERGHUIS, Bojan, BURNS, Norman, STAKER, Bryan
Format: Patent
Sprache:eng
Schlagworte:
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
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Beschreibung
Zusammenfassung:Disclosed herein are methods and systems for detection and discrimination of optical signals from a densely packed substrate. These may have broad applications for biomolecule detection near or below the diffraction limit of optical systems, including in improving the efficiency and accuracy of polynucleotide sequencing applications.