PYRAZOLONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS

PYRAZOLONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS

The disclosure relates to compounds of formula I, which are formyl peptide 2 (FPR2) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and rel...

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Bibliographische Detailangaben
Hauptverfasser: Shirude, Pravin Sudhaka, Kick, Ellen K, Chattopadhyay, Amit Kumar, Clark, Charles G, Pi, Zulan, Johnson, James A, Smallheer, Joanne M, Wurtz, Nicholas R, Seshadri, Balaji Kumar, Valente, Meriah Neissel
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The disclosure relates to compounds of formula I, which are formyl peptide 2 (FPR2) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.