NOVEL MULTIPARTICULATE PHARMACEUTICAL COMPOSITION OF TAMSULOSIN AND SOLIFENACIN

The present invention relates to a novel multiparticulate pharmaceutical composition for oral administration with a controlled dissolution rate. The composition comprises Tamsulosin hydrochloride in modified release form and Solifenacin succinate in mmediate release form, wherein the core comprises...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DAUD, Anwar, RATHOD, Yuvraj, JADHAV, Anil, KEDAR, Uttam, MAINDE, Chandrashekhar
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a novel multiparticulate pharmaceutical composition for oral administration with a controlled dissolution rate. The composition comprises Tamsulosin hydrochloride in modified release form and Solifenacin succinate in mmediate release form, wherein the core comprises Tamsulosin hydrochloride and an outer immediate layer comprises Solifenacin succinate. According to the present invention, the instant formulation release the drug at predetermined rate and prevent dose dumping as well as improving the patient compliance.