TABLET FORMULATION FOR CGRP ACTIVE COMPOUNDS

The present invention is directed to compositions comprising an extrudate or solid solution of a compound, or a salt thereof, of Formula I (API):wherein "Ra" is independently -H or -F, in a water-soluble polymer matrix which further comprises a disintegration system allowing a tablet made...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Allain, Leonardo Resende, Eickhoff, W. Mark, Lupton, Lisa, Xu, Wei, Nofsinger, Rebecca, Xi, Hanmi, Johnson, Mary Ann, Ikeda, Craig B, Flanagan, JR., Francis J, Marota, Melanie, Brown, Chad D, Patel, Paresh B
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention is directed to compositions comprising an extrudate or solid solution of a compound, or a salt thereof, of Formula I (API):wherein "Ra" is independently -H or -F, in a water-soluble polymer matrix which further comprises a disintegration system allowing a tablet made therefrom to rapidly disintegrate in the environment in which the API is to be released.