METHODS OF TREATING THYROID EYE DISEASE AND GRAVES' ORBITOPAHY USING INTERLEUKIN-17 (IL-17) ANTAGONISTS

METHODS OF TREATING THYROID EYE DISEASE AND GRAVES' ORBITOPAHY USING INTERLEUKIN-17 (IL-17) ANTAGONISTS

The present disclosure relates to methods for treating Thyroid Eye Disease (e.g., Graves' Orbitopathy) using Interleukin (IL)-17 antagonists, e.g., secukinumab. Also disclosed herein are IL-17 antagonists, e.g., IL-17 antibodies, such as secukinumab, for treating patients having Thyroid Eye Dis...

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Bibliographische Detailangaben
Hauptverfasser: MENDELSON, Meryl, KAHALY, Georges Jean, REINHARDT, Maximilian, BRUIN, Gerard
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Beschreibung
Zusammenfassung:The present disclosure relates to methods for treating Thyroid Eye Disease (e.g., Graves' Orbitopathy) using Interleukin (IL)-17 antagonists, e.g., secukinumab. Also disclosed herein are IL-17 antagonists, e.g., IL-17 antibodies, such as secukinumab, for treating patients having Thyroid Eye Disease (e.g., Graves' Orbitopathy), as well as medicaments, dosing regimens, pharmaceutical formulations, dosage forms, and kits for use in the disclosed uses and methods.