METHODS OF MAKING WEE1 INHIBITOR COMPOUNDS

A process is provided for making a WEE1 inhibitor of the formula (1A) useful in the treatment of conditions characterized by excessive cellular proliferation, such as cancer. In some embodiments, processes are provided for making intermediate compounds of the formulae (3), (5) and (6) as defined her...

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Bibliographische Detailangaben
Hauptverfasser: Abraham, Sunny, Wu, Tao, Bunker, Kevin Duane, Hopkins, Chad Daniel, Boren, Brant Clayton, Pratt, Benjamin, Zhu, Shuguang, Huang, Peter Qinhua, Boga, Sobhana Babu
Format: Patent
Sprache:eng
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Zusammenfassung:A process is provided for making a WEE1 inhibitor of the formula (1A) useful in the treatment of conditions characterized by excessive cellular proliferation, such as cancer. In some embodiments, processes are provided for making intermediate compounds of the formulae (3), (5) and (6) as defined herein.