COMPOSITIONS AND METHODS FOR MOLECULAR LABELING

The invention provides barcode libraries and methods of making and using them including obtaining a plurality of nucleic acid constructs in which each construct comprises a unique N-mer and a functional N-mer and segregating the constructs into a fluid compartments such that each compartment contain...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Link, Darren R, Watson, Andrew, Samuels, Michael L, Olson, Jeffrey Charles, Brown, Keith
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides barcode libraries and methods of making and using them including obtaining a plurality of nucleic acid constructs in which each construct comprises a unique N-mer and a functional N-mer and segregating the constructs into a fluid compartments such that each compartment contains one or more copies of a unique construct. The invention further provides methods for digital PCR and for use of barcode libraries in digital PCR.