ANTIBODY SPECIFIC TO NECTIN CELL ADHESION MOLECULE 4 AND USES THEREOF

ANTIBODY SPECIFIC TO NECTIN CELL ADHESION MOLECULE 4 AND USES THEREOF

The present disclosure relates to a modified antibody, or antigen-binding fragment thereof, specific for nectin cell adhesion molecule 4 (nectin-4). The present disclosure also relates to a method of detecting or diagnosing whether a subject has, or is at risk of developing a tumor, or assessing a p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TSAI, Bor-Yu, HUANG, Shin-Tsung, HSU, Wei-Ting
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure relates to a modified antibody, or antigen-binding fragment thereof, specific for nectin cell adhesion molecule 4 (nectin-4). The present disclosure also relates to a method of detecting or diagnosing whether a subject has, or is at risk of developing a tumor, or assessing a prognosis of a tumor and a pharmaceutical composition for use in treating, prophylactic treating and/or preventing tumor in a subject afflicted with the tumor.