PD-L1 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF

PD-L1 VARIANT IMMUNOMODULATORY PROTEINS AND USES THEREOF

Provided herein are immunomodulatory proteins comprising variant PD-L1 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provid...

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Bibliographische Detailangaben
Hauptverfasser: MAURER, Mark F, KORNACKER, Michael, ARDOUREL, Dan, DEMONTE, Daniel William, SWANSON, Ryan, KUJIPER, Joseph L
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
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ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Provided herein are immunomodulatory proteins comprising variant PD-L1 and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.