MULTI-LAYER NANOFIBER SCAFFOLDS

Provided are 3D cell culture scaffolds, 3D nanofiber scaffolds, and edible 3D nanofiber scaffolds for cultured meat. Described is a 3D cell culture scaffold including a plurality of laminated nanofiber layers. Each layer is formed by an array of nanofibers. The diameter of each of the nanofibers in...

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Bibliographische Detailangaben
Hauptverfasser:	Yadavalli, Nataraja S, Asheghali, Darya, Blevins, Brianna, Jahan, Ummay Mowshome, Minko, Sergiy, Reukov, Vladimir, Tokarev, Alexander
Format:	Patent
Sprache:	eng
Schlagworte:	ADDITIVE MANUFACTURING TECHNOLOGY ADDITIVE MANUFACTURING, i.e. MANUFACTURING OFTHREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVEAGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING,STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FOODS OR FOODSTUFFS HUMAN NECESSITIES MANUFACTURE OR TREATMENT OF NANOSTRUCTURES MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NANOTECHNOLOGY PERFORMING OPERATIONS PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS PROTEIN COMPOSITIONS FOR FOODSTUFFS SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES SPIRITS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES TRANSPORTING VINEGAR WINE WORKING-UP PROTEINS FOR FOODSTUFFS
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Beschreibung
Zusammenfassung:	Provided are 3D cell culture scaffolds, 3D nanofiber scaffolds, and edible 3D nanofiber scaffolds for cultured meat. Described is a 3D cell culture scaffold including a plurality of laminated nanofiber layers. Each layer is formed by an array of nanofibers. The diameter of each of the nanofibers in the arrays can have a tunable, predetermined diameter and can be formed from materials including a natural polymer, a synthetic polymer, a biocompatible material, or a combination thereof. Each of the nanofibers in the arrays can have controlled alignment, angle, and spacing from one another. The layers can be spaced by spacer fibers or spacer sheets. The scaffold can have a porosity of about 50% to 99%. Edible 3D scaffolds for cultured meat are also provided where the nanofibers and spacers are edible.