FACTOR XI ACTIVATION INHIBITORS

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XI activat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Debenham, John S, Wei, Lan, Ali, Amjad, Yang, Dexi, Tatosian, Daniel A, Gao, Ying-Duo, Hruza, Alan, Kuang, Rongze, HICKS, Jacqueline D, Nizner, Peter
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XI activation inhibitors.