COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS

Compositions and methods for the treatment of bacterial infections include conjugates containing an Fc domain covalently linked to one or more monomers of cyclic heptapeptides or one or more dimers of cyclic heptapeptides. In particular, conjugates can be used in the treatment of bacterial infection...

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Hauptverfasser: CHEN, Zhi-Yong, BORCHARDT, Allen, BRADY, Thomas P, AKERS-RODRIGUEZ, Suzanne, NONCOVICH, Alain, LEVIN, James, DO, Quyen-Quyen Thuy, BLIZZARD, Timothy, DOEHRMANN, Simon, JIANG, Wanlong, BALKOVEC, James M, FORTIER, Joanne M, TARI, Leslie W, BENSEN, Daniel C, LAM, Thanh
Format: Patent
Sprache:eng
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Zusammenfassung:Compositions and methods for the treatment of bacterial infections include conjugates containing an Fc domain covalently linked to one or more monomers of cyclic heptapeptides or one or more dimers of cyclic heptapeptides. In particular, conjugates can be used in the treatment of bacterial infections caused by Gram-negative bacteria.