IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF

IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF

The present application relates to imidazolidinone derivatives and medical use thereof, and in particular relates to pyrimidine derivatives represented by general formula (I), or stereoisomers, solvates, metabolites, prodrugs, pharmaceutically acceptable salts or co-crystals thereof, a pharmaceutica...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CHU, Hongzhu, HE, Lvxue, YAN, Jie, LIU, Bing, SUN, Yi, WEI, Yonggang, WANG, Meiwei, XU, Xuezhen, SU, Guizhuan, LEI, Feiquan, HE, Yang
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present application relates to imidazolidinone derivatives and medical use thereof, and in particular relates to pyrimidine derivatives represented by general formula (I), or stereoisomers, solvates, metabolites, prodrugs, pharmaceutically acceptable salts or co-crystals thereof, a pharmaceutical composition comprising the same, and use of the compound or pharmaceutical composition according to the present application in the manufacture of a medicament for treatment of cancer.