Methods of Inhibiting SARS-CoV-2 Replication and Treating Corona Virus Disease 2019

The invention relates to methods of treating COVID-19 in a patient by administering therapeutically effective amounts of certain SARS-CoV-2 inhibitor compounds or pharmaceutical compositions containing them to a patient in need thereof. The invention also relates to inhibiting SARS-CoV-2 coronavirus...

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Bibliographische Detailangaben
Hauptverfasser:	Ticehurst, Martyn David, Burke, Benjamin Joseph, Hoffman, Robert Louis, O'Brien Laramy, Matthew Nathan, Sullivan, Bradley Paul, Pencheva, Klimentina Dimitrova, Lillis, Jonathan Richard, Hawking, Emma Louise, Thiel, Andrew John, Bezawada, Padmavani, Kania, Robert Steven
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to methods of treating COVID-19 in a patient by administering therapeutically effective amounts of certain SARS-CoV-2 inhibitor compounds or pharmaceutical compositions containing them to a patient in need thereof. The invention also relates to inhibiting SARS-CoV-2 coronavirus viral replication activity comprising contacting SARS-CoV-2-related coronavirus protease with a therapeutically effective amount of a SARS-Cov-2 protease inhibitor, such as a SARS-Cov-2 3CL protease inhibitor and compositions comprising the same