METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS

METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS

This disclosure describes an economical and scalable method and process to synthesize the Calcium sensing receptor (CaSR) modulating agent 2-methyl-5-((2R,4S)-2-(((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoic acid, its intermediates and pharmaceutically acceptable salts therefor. Us...

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Hauptverfasser: SACHIN, Subhash Ingawale, SITARAM RAMBHAU, Barve, AMIT, Dattatray Karche, KAMBOJ, Rajender Kumar, RAJESH, Bhavani Shankar, SANTOSHKUMAR, Shankar Dange, PADIYA, Kamlesh Jyotindra, NAIK, Kumar Ram, RAJENDRA, Ganpati Powar, PRABAKARAN, Kamalakannan
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:This disclosure describes an economical and scalable method and process to synthesize the Calcium sensing receptor (CaSR) modulating agent 2-methyl-5-((2R,4S)-2-(((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoic acid, its intermediates and pharmaceutically acceptable salts therefor. Uses of said intermediates for synthesis of compounds which may be intermediates to the synthesis of 2-methyl-5-((2R,4S)-2-(((R)-1-(naphthalen-1-yl)ethyl)amino)methyl)chroman-4-yl)benzoic acid are also described herein.